Shelter from danger or hardship (6)
I believe the answer is:
asylum
'shelter from danger or hardship' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for asylum that I've seen before include "Protection given to political refugee" , "Place of refuge, sanctuary" , "Madhouse" , "'Refuge, sanctuary (6)'" , "Shelter given to refugee" .)