Crossword Genius

Sign of infection on the rise in marsupials? (3)

Ross

I believe the answer is:

pus

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'sign of infection' is the definition.
Although both the answer and definition are singular nouns, I cannot understand how they can define each other.

'the rise in marsupials' is the wordplay.
'the rise' says the letters should be written in reverse.
'in' indicates the answer is hidden within the clue.
'sup' can be found hidden inside 'marsupials'.
'sup' reversed gives 'PUS'.

'on' is the link.

Can you help me to learn more?

(Other definitions for pus that I've seen before include "Fluid, a product of inflammation" , "Fluid in infected tissue" , "Liquid produced in infected tissue" , "Discharge from wound" , "Fluid formed by suppuration" .)

I've seen this clue in the Irish Times.
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