Slovenly woman misplaced last rent (8)
I believe the answer is:
slattern
'slovenly woman' is the definition.
(synonyms)
'misplaced last rent' is the wordplay.
'misplaced' indicates anagramming the letters (letters in the wrong places).
'last'+'rent'='lastrent'
'lastrent' with letters rearranged gives 'SLATTERN'.
(Other definitions for slattern that I've seen before include "Sloven" , "Drab" , "Grubby woman" , "Cow" , "Dirty and untidy woman" .)