Small room, outsize instruments (6)
I believe the answer is:
cellos
'instruments' is the definition.
(cello is a kind of instrument)
'small room outsize' is the wordplay.
'small room' becomes 'cell' (eg a prison cell).
'outsize' becomes 'os'.
'cell'+'os'='CELLOS'
(Another definition for cellos that I've seen is " Large stringed instruments".)
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