Sound of saint leaving a studio (5)
I believe the answer is:
audio
'sound' is the definition.
(audio means sound)
'saint leaving a studio' is the wordplay.
'saint' becomes 'st' (abbreviation).
'leaving' suggests deleting specific letters.
'a'+'studio'='astudio'
'astudio' with 'st' taken out is 'AUDIO'.
'of' acts as a link.
(Other definitions for audio that I've seen before include "Reproduction of recorded sound" , "Sound recording" , "Prefix relating to sound" , "Television sound" , "- - visual aids" .)