Stick end of stick in waste pipe (6)
I believe the answer is:
skewer
'stick' is the definition.
(thesaurus)
'end of stick in waste pipe' is the wordplay.
'end of' says to take the final letters.
'in' means one lot of letters goes inside another.
'waste pipe' becomes 'sewer' (sewer is a kind of waste pipe).
The final letter of 'stick' is 'k'.
'k' placed inside 'sewer' is 'SKEWER'.
(Other definitions for skewer that I've seen before include "more asymmetrical?" , "Metal pin for meat" , "Stick on which kebab is cooked" , "Criticise pointedly" , "Transfix" .)