Stitched up in every direction (4)
I believe the answer is:
sewn
I believe this clue is a double definition.
'stitched up' is the first definition.
(I've seen this before)
'every direction' is the second definition.
(compass directions)
'in' acts as a link.
(Other definitions for sewn that I've seen before include "joined together" , "Darned" , "Joined with stitches" , "Needled" , "Joined by stitching" .)