Take a break every year and exercise (5)
I believe the answer is:
pause
'take a break' is the definition.
(synonyms)
'every year and exercise' is the wordplay.
'every year' becomes 'pa' (per annum).
'and' is a charade indicator (letters next to each other).
'exercise' becomes 'use' (synonyms).
'pa'+'use'='PAUSE'
(Other definitions for pause that I've seen before include "Take a break" , "Wait" , "Short break" , "Short delay" , "Stop briefly, take ten" .)