Take off for southern tour (5)
I believe the answer is:
strip
'take off' is the definition.
(stripping is a kind of taking off)
'southern tour' is the wordplay.
'southern' becomes 's' (abbreviation).
'tour' becomes 'trip' (I've seen this in another clue).
's'+'trip'='STRIP'
'for' acts as a link.
(Other definitions for strip that I've seen before include "may be torn off in anger?" , "Take off one's clothes" , "Undress a long narrow piece" , "Team kit" , "Remove clothing" .)