Talks wildly in a most strange way (5)
I believe the answer is:
rants
'talks wildly' is the definition.
(I've seen this in another clue)
'a most strange way' is the wordplay.
I cannot really understand how this works, but
'a' could be 'an' and 'an' is found within the answer.
'way' could be 's' (Compass direction - South) and 's' is present in the answer.
This may be the basis of the clue (or it may be nonsense).
'in' is the link.
Can you help me to learn more?
(Other definitions for rants that I've seen before include "Loud pompous declamations" , "Loud bombastic declamations" , "Raves" , "Noisily declaims" .)