Tell, once again, a confused tale (6)
I believe the answer is:
relate
'tell' is the definition.
(as in to tell or relate a story)
'once again a confused tale' is the wordplay.
'once again' becomes 're' (prefix in verbs).
'a confused' indicates an anagram.
'tale' with letters rearranged gives 'late'.
're'+'late'='RELATE'
(Other definitions for relate that I've seen before include "Narrate or associate" , "Tell (a story)" , "Make a logical or causal connection" , "Give account of (story)" , "link" .)