Textile business originally nonprofit (5)
I believe the answer is:
linen
'textile' is the definition.
(I know that linen is a type of textile)
'business originally nonprofit' is the wordplay.
'business' becomes 'line' (as in someone's line of work).
'originally' indicates taking the first letters.
The first letter of 'nonprofit' is 'n'.
'line'+'n'='LINEN'
(Other definitions for linen that I've seen before include "bedding" , "bedsheets?" , "Cloth made from flax" , "Such paper" , "sheets, perhaps" .)