The dangers of working with pliers (6)
I believe the answer is:
perils
'the dangers' is the definition.
(peril is a kind of danger)
'working with pliers' is the wordplay.
'working with' indicates an anagram (working with the letters).
'pliers' with letters rearranged gives 'PERILS'.
'of' is the link.
(Other definitions for perils that I've seen before include "'Dangers, hazards (6)'" , "Dangers, risks" .)