The ends of a journey and not getting sickness: that's unusual (8)
I believe the answer is:
abnormal
'unusual' is the definition.
(similar in meaning)
'the ends of a journey and not getting sickness' is the wordplay.
'the ends of a journey' becomes 'ab' (I can't explain this - if you can you should believe this answer much more).
'and not' becomes 'nor' ('nor' means 'and also not').
'getting' means one lot of letters go next to another.
'sickness' becomes 'mal' (I've seen this before).
'ab'+'nor'+'mal'='ABNORMAL'
'that's' acts as a link.
Can you help me to learn more?
(Other definitions for abnormal that I've seen before include "Deviating from the usual" , "Exceptional; strange" , "Deviant, different from the usual" , "Deviating from the standard" , "Different from what is usual or accepted" .)