Crossword Genius

To no avail (2,4)

Ross

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6

2,4

'to no avail' is the definition.
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This is the entire clue.

(Other definitions for futile that I've seen before include "In vain, a waste of time" , "Useless, a waste of effort" , "Ineffectual, vain" , "Ineffective" , "Fruitless" .)

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