Trading hub located in centre potentially (8)
I believe the answer is:
entrepot
'trading hub' is the definition.
(term for a port city)
'located in centre potentially' is the wordplay.
'located in' indicates the answer is hidden within the clue.
'ENTREPOT' is hidden in the letters of 'centre potentially'.
(Other definitions for entrepot that I've seen before include "Import/export warehouse, port" , "Bonded warehouse; port" , "Storehouse" , "Trading port" .)