Uproar in place to retire: left before morning (6)
I believe the answer is:
bedlam
'uproar' is the definition.
(I've seen this before)
'place to retire left before morning' is the wordplay.
'place to retire' becomes 'bed' (I've seen this in another clue).
'left' becomes 'l' (common abbreviation).
'before' says to put letters next to each other.
'morning' becomes 'am' (as in 12:00 AM).
'bed'+'l'+'am'='BEDLAM'
'in' acts as a link.
(Other definitions for bedlam that I've seen before include "State of extreme confusion and uproar" , "Mayhem" , "Blamed for intolerable noise" , "Ambled (anag)" , "Madhouse - uproar" .)