Values seem set for a change (7)
I believe the answer is:
esteems
'values' is the definition.
(esteem can mean to value)
'seem set for a change' is the wordplay.
'for a change' is an anagram indicator.
'seem'+'set'='seemset'
'seemset' with letters rearranged gives 'ESTEEMS'.
(Other definitions for esteems that I've seen before include "Values highly" , "Regards highly" , "Prizes or admires" , "Treasures" .)