Wealth from work uncle wasted at end of life (8)
I believe the answer is:
opulence
'wealth' is the definition.
(opulence is a kind of wealth)
'work uncle wasted at end of life' is the wordplay.
'work' becomes 'op' (abbreviation for opus).
'wasted' indicates an anagram.
'at end of' says to take the final letters.
The last letter of 'life' is 'e'.
'uncle' with letters rearranged gives 'ulenc'.
'op'+'ulenc'+'e'='OPULENCE'
'from' acts as a link.
(Other definitions for opulence that I've seen before include "State of affluence and luxury" , "Means" , "Ostentatious luxury" , "Luxury, sumptuousness" , "Great wealth" .)