Welcome S African stringed instrument (6)
I believe the answer is:
salute
'welcome' is the definition.
(both are a kind of greeting)
's african stringed instrument' is the wordplay.
's african' becomes 'sa'.
'stringed instrument' becomes 'lute' (lute is a type of stringed instrument).
'sa'+'lute'='SALUTE'
(Other definitions for salute that I've seen before include "A greeting, often military" , "Hail, greet" , "Pay tribute to; greet" , "Kind of welcome" , "Greet with a sign" .)