What buds do sometimes on vacation in Orlando? (7)
I believe the answer is:
blossom
'what buds do' is the definition.
(I've seen this in another clue)
'sometimes on vacation in orlando?' is the wordplay.
'on vacation' says to hollow out the word (remove centre letters).
'in' means one lot of letters goes inside another.
'orlando?' becomes 'Bloom' (Orlando Bloom is an actor).
'sometimes' with its centre removed is 'ss'.
'ss' going inside 'bloom' is 'BLOSSOM'.
(Other definitions for blossom that I've seen before include "May beauty" , "Do well" , "Thrive" , "Yield flowers" , "Flourish and prosper" .)