Which wine could make men so ill? (8)
I believe the answer is:
semillon
'which wine' is the definition.
I don't know anything about this answer so I can't judge whether it can be defined by this definition.
'make men so ill?' is the wordplay.
'make' is an anagram indicator.
'men'+'so'+'ill'='mensoill'
'mensoill' with letters rearranged gives 'SEMILLON'.
'could' acts as a link.
Can you help me to learn more?
(Other definitions for semillon that I've seen before include "alcoholic drink" , "Wine grape" .)