Zest coming from wee drop of Laphroaig (4)
I believe the answer is:
peel
'zest' is the definition.
(I've seen this in another clue)
'wee drop of laphroaig' is the wordplay.
'wee' becomes 'pee' (both can mean to urinate).
'drop of' indicates taking the first letters (the smallest possible amount of the word).
The first letter of 'laphroaig' is 'l'.
'pee'+'l'='PEEL'
'coming from' is the link.
(Other definitions for peel that I've seen before include "zest, getting out of this scrape?" , "Strip off -- Manx port" , "Skin of eg an orange" , "Lemon skin" , "PM once; remove skin" .)