A tiny girl's furious complaint (10)
I believe the answer is:
laryngitis
'complaint' is the definition.
(laryngitis is a kind of disease)
'a tiny girl's furious' is the wordplay.
'furious' indicates an anagram.
'a'+'tiny'+'girls'='atinygirls'
'atinygirls' is an anagram of 'LARYNGITIS'.
(Other definitions for laryngitis that I've seen before include "Inflammation of the vocal cords" , "Inflammation of part of throat" , "Sore throat" , "Throat infection" , "Inflammation making it difficult to speak" .)