Abandoned, many felt irritated (7)
I believe the answer is:
ditched
'abandoned' is the definition.
(ditching is a kind of abandoning)
'many felt irritated' is the wordplay.
I cannot quite see how this works, but
'many' could be 'd' and 'd' is located in the answer.
'irritated' could be 'itched' (itching is a kind of irritating) and 'itched' is found within the answer.
No letters remain.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for ditched that I've seen before include "Of plane, made forced landing on sea" , "Dumped" , "Got rid of" , "Left in the lurch or landed plane in sea" .)