Agile duo animated in discussion (8)
I believe the answer is:
dialogue
'discussion' is the definition.
(I've seen this before)
'agile duo animated' is the wordplay.
'animated' indicates an anagram.
'agile'+'duo'='agileduo'
'agileduo' with letters rearranged gives 'DIALOGUE'.
'in' acts as a link.
(Other definitions for dialogue that I've seen before include "Discussion" , "Agile duo in conversation" , "brought into play perhaps" , "Lines spoken in films, books etc" , "Conversation as in a play" .)