Be hot under the collar (6)
(Other definitions for fume that I've seen before include "Emit smoke or seethe with anger" , "Feel great anger" , "Express great anger" , "A - cupboard may be found in chemistry lab" , "Smoke and be angry" .)
'be hot under the collar' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for seethe that I've seen before include "Smoulder" , "Be extremely angry" , "get very agitated" , "Boil; be crowded with moving people" , "Boil; fume with suppressed rage" .)