Cry for help involving Spain and a girl mixed up in harems (9)

'harems' is the definition.
('seraglio' can be a synonym of 'harem')

'cry for help involving spain and a girl mixed up' is the wordplay.
'cry for help' becomes 'sos' (an SOS message sent in an emergency).
'involving' means one lot of letters goes inside another.
'spain' becomes 'e' (abbreviation for Espana).
'and' says to put letters next to each other.
'mixed up' indicates anagramming the letters.
'e'+'a'+'girl'='eagirl'
'eagirl' is an anagram of 'eragli'.
'sos' placed around 'eragli' is 'SERAGLIOS'.

'in' acts as a link.