Double murder in US bureau (6)
I believe the answer is:
office
'us bureau' is the definition.
'office' can be an answer for 'bureau' (synonyms). I am not certain of the 'us' bit.
'double murder' is the wordplay.
'double' becomes 'off' (I can't justify this - if you can you should believe this answer much more).
'murder' becomes 'ice' (slang term).
'off'+'ice'='OFFICE'
'in' acts as a link.
Can you help me to learn more?
(Other definitions for office that I've seen before include "Post - place of work" , "Workplace for clerks" , "Business premises" , "Place for administrative business" , "Administrative unit" .)