First lady after Hillary (5)
I believe the answer is:
laura
'first lady after hillary' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for laura that I've seen before include "1944 American film noir directed by Otto Preminger" , "US First Lady" , "Cells of a group of recluses" , "- Ashley, Welsh clothing and furniture designer" , "Girl's name" .)