Florida resort without a role for a soprano (4)
I believe the answer is:
Here is my best explanation:
'role for a soprano' is the definition.
'florida resort without a' is the subsidiary indication.
'florida resort' becomes 'miami'.
'without' suggests deleting specific letters.
'miami' with 'a' removed is 'mimi'.
(Other definitions for mimi that I've seen before include "Bohemian girl", "I'm, I'm mad about the heroine in 'La Boheme'", "Her tiny hand was frozen (Puccini)", "Puccini's seamstress", "'They call me - - ' , (Lucia)", "La Boheme character (whose tiny hand is frozen)", "Starving character of "La Boheme"", "Heroine of La Boheme", "Puccini heroine" and "I'm upset twice by the operatic girl".)