For powerful Florentine family, Demi whipped 101 (6)
I believe the answer is:
medici
'for powerful florentine family' is the definition.
I can't tell whether this defines the answer.
'demi whipped 101' is the wordplay.
'whipped' is an anagram indicator.
'101' becomes 'CI' (roman numerals).
'demi' with letters rearranged gives 'medi'.
'medi'+'ci'='MEDICI'
Can you help me to learn more?
(Other definitions for medici that I've seen before include "Italian family who ruled Florence in the 15th century" , "Noted Florentine family" , "Well-known European family" , "Powerful old Italian family" , "Great Italian family" .)