Get rid of me over anagramming (6)
I believe the answer is:
remove
'get rid of' is the definition.
('remove' can be a synonym of 'get rid of')
'me over anagramming' is the wordplay.
'anagramming' indicates anagramming the letters (I've seen 'anagram' mean this).
'me'+'over'='meover'
'meover' is an anagram of 'REMOVE'.
(Other definitions for remove that I've seen before include "class in school" , "Abstract" , "Bunter's form" , "Take away or extract" , "Subtract" .)