Got us upset with relish (5)
I believe the answer is:
gusto
'relish' is the definition.
('gusto' can be a synonym of 'relish')
'got us upset' is the wordplay.
'upset' indicates an anagram.
'got'+'us'='gotus'
'gotus' with letters rearranged gives 'GUSTO'.
'with' is the link.
(Other definitions for gusto that I've seen before include "Obvious enthusiasm" , "Showing zest" , "Hearty enjoyment" , "Relish; vigour" , "Zest and enjoyment in doing something" .)