It may be there in space (5)
I believe the answer is:
ether
'space' is the definition.
(thesaurus)
'it may be there' is the wordplay.
'it may be' is an anagram indicator (I've seen this in other clues).
'there' with letters rearranged gives 'ETHER'.
'in' is the link.
(Other definitions for ether that I've seen before include "Highly flammable liquid once used as an anaesthetic" , "Some were put out by this" , "Old anaesthetic -- three (anag)" , "Gas - air - space" , "Colourless volatile highly inflammable liquid" .)