Lacking nucleus, fermenting yeast is swelling (4)
I believe the answer is:
stye
'is swelling' is the definition.
(I've seen this before)
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for stye that I've seen before include "Eyelid sore" , "irritation to the viewer" , "It pains viewer" , "Inflamed swelling on the edge of an eyelid" , "Eye sore" .)