Lyre playing in bank (4)
I believe the answer is:
rely
'bank' is the definition.
(to bank on something is to rely on it)
'lyre playing' is the wordplay.
'playing' indicates an anagram.
'lyre' anagrammed gives 'RELY'.
'in' is the link.
(Other definitions for rely that I've seen before include "Lyre (anag.)" , "Depend confidently (on)" , "Depend on with confidence" , "Bank (on someone)" , "City with cathedral" .)