Man-made fabric (5)
I believe the answer is:
nylon
'man-made fabric' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for nylon that I've seen before include "Tights material" , "Unaccompanied part song" , "where ladder can appear?" , "Strong, resilient, synthetic fibre" , "Man-made material" .)