Meat turned up in middle of road in US city (5)
I believe the answer is:
omaha
'us city' is the definition.
(I've seen this before)
'meat turned up in middle of road' is the wordplay.
'meat' becomes 'ham' (ham is a kind of meat).
'turned up' says the letters should be written backwards.
'in' means one lot of letters goes inside another.
'middle of' indicates the central letters.
The middle letters of 'road' are 'oa'.
'ham' back-to-front is 'mah'.
'mah' inserted into 'oa' is 'OMAHA'.
'in' is the link.
(Other definitions for omaha that I've seen before include "Largest city in Nebraska" , "American-Indians" , "American Indian" , "US city; D-Day 16" , "US 1944 D-Day landing beach" .)