Crossword Genius

My rise has been ruined because of the depression (6)

Ross

I believe the answer is:

misery

I'm a little stuck... Click here to teach me more about this clue!

'the depression' is the definition.
(thesaurus)

'my rise has been ruined because' is the wordplay.
'my rise' anagrams to 'MISERY'.
However, I am not clear how the anagram is indicated.

'of' acts as a link.

Can you help me to learn more?

(Other definitions for misery that I've seen before include "Distress, wretchedness" , "Great suffering" , "Feeling of great unhappiness" , "Wretchedness, suffering" , "Wretched unhappiness" .)

I've seen this clue in The Irish Independent.
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