Name potholer lost in remote region (5,4)
I believe the answer is:
north pole
'remote region' is the definition.
'name potholer lost' is the wordplay.
'name' becomes 'n' (common abbreviation e.g. on forms).
'lost' indicates anagramming the letters.
'potholer' is an anagram of 'orthpole'.
'n'+'orthpole'='NORTH POLE'
'in' acts as a link.
(Other definitions for north pole that I've seen before include "I'm on top of the world" , "a really cold environment" , "Icy area" , "One end of earth's axis" , "as Pooh found?" .)