News in Brussels on current malaise (5)
I believe the answer is:
ennui
'malaise' is the definition.
(thesaurus)
'news in brussels on current' is the wordplay.
'news' becomes 'nn' (n is common abbrev for new, news can be plural).
'in' indicates putting letters inside.
'brussels' becomes 'EU' (European Parliament is based in Brussels).
'on' says to put letters next to each other.
'current' becomes 'I' (symbol for electric current).
'nn' going within 'eu' is 'ennu'.
'ennu'+'i'='ENNUI'
(Other definitions for ennui that I've seen before include "What's tedious and instils such listlessness" , "Lack of interest" , "Boredom, dullness" , "Boredom, listlessness" , "Mental weariness" .)