Not at all, not in any way (5)
I believe the answer is:
nohow
I believe this clue is a double definition.
'not at all' is the first definition.
(synonyms)
'not in any way' is the second definition.
(I've seen this in another clue)
(Other definitions for nohow that I've seen before include "Never" , "Definitely not" , "Not by any means, informally" , "not at all the American way?" , "Under no circumstances (as Tweedledum said)" .)