Respected, as some guide meets everybody on the way up (8)
I believe the answer is:
esteemed
'respected' is the definition.
('esteem' can be a synonym of 'respect')
'some guide meets everybody on the way up' is the wordplay.
'some' indicates a hidden word (some of the parts of the word are used).
'on the way up' is a reversal indicator.
'demeetse' is hidden within 'guide meets everybody'.
'demeetse' back-to-front is 'ESTEEMED'.
'as' acts as a link.
(Other definitions for esteemed that I've seen before include "Highly respected like good customer" , "Well-regarded" , "Highly regarded" , "Dear" , "Respected and appreciated like customer" .)