Setting up shop? (13)
I believe the answer is:
establishment
I believe this clue is a double definition.
'setting up' is the first definition.
(I've seen this before)
'shop?' is the second definition.
(shop is a kind of establishment)
(Other definitions for establishment that I've seen before include "Formation" , "Permanent staff; business; household" , "Institution; (the) ruling classes" , "Action of setting up on a permanent basis" , "Permanent staff - powerful class" .)