Soreness, agony (4)
I believe the answer is:
pain
This clue is a double definition.
'soreness' is the first definition.
(I've seen this in another clue)
'agony' is the second definition.
(I've seen this before)
(Other definitions for pain that I've seen before include "Hurt feeling" , "Suffering of body or mind" , "Bodily suffering or mental anguish" , "great discomfort" , "Mental distress" .)