Stupidest direction: rid face of pimples with testosterone (8)

I believe the answer is:

simplest

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'stupidest' is the definition.
Both the answer and definition are superlative adjectives. Perhaps there's a link between them I don't understand?

I don't understand the remainder of the clue.

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(Other definitions for simplest that I've seen before include "Easiest, least complex" , "Misspelt in the least complicated way" , "Least complex or complicated" , "US TV award" .)

I've seen this clue in the Sydney Morning Herald.

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