TV programme in the main sent round with no changes made (2,2,5)
I believe the answer is:
as it comes
'with no changes made' is the definition.
(as it comes, ie without changes)
'tv programme in the main sent round' is the wordplay.
'tv programme' becomes 'sitcom' (type of TV programme).
'in the' is an insertion indicator.
'main' becomes 'sea' (the main is an old name for the sea).
'sent round' says the letters should be written backwards.
'sea' in reverse letter order is 'aes'.
'sitcom' inserted into 'aes' is 'AS IT COMES'.
(Other definitions for as it comes that I've seen before include "however produced" , "the way it's made" , "in no particular order" .)