What sewer did in street caused irritation (8)
I believe the answer is:
stitched
'what sewer did' is the definition.
(sewer meaning someone who sews)
'street caused irritation' is the wordplay.
'street' becomes 'st' (abbreviation).
'caused irritation' becomes 'itched'.
'st'+'itched'='STITCHED'
'in' is the link.
(Other definitions for stitched that I've seen before include "Attached with thread" , "Bound" , "Joined up" , "Fasten by sewing" , "Fastened by sewing" .)