With ecstasy seized, arrests up in state again (8)
I believe the answer is:
reassert
'up in state again' is the definition.
I can't judge whether this defines the answer.
'with ecstasy seized arrests' is the wordplay.
I cannot really see how this works, but
'ecstasy' could be 'e' (informal term for the drug) and 'e' is found within the answer.
an anagram of 'arrests' is 'rassert' which is present in the left over letters.
No letters remain.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for reassert that I've seen before include "Again make statement" , "Pronounce once more" , "State with force" , "Make one's presence felt once more" .)